This article outlines a potential synergy between sustainability and well-being research. Currently aims within well-being and sustainability research focus on increasing well-being. First, sustainability is defined and important concepts within it highlighted, that is, aims, interdependencies, constraints, values and balanced adaptive processes. It is suggested that positioning well-being more clearly within the sustainability framework can enhance the role of sustainability; for example, in terms of aims and monitoring progress. In turn, the sustainability framework outlined, guides the second part of the article, illustrating how it can reciprocally enhance well-being research. That is, comprehensive empirical, evolutionary, cross-cultural, and self-conceptual evidence illustrate individuals’ interdependencies with other people and nature. Despite this, contemporary hedonic and eudaimonic well-being approaches and accompanying measures are demonstrated to be isolating; investigating well-being individualistically and in a decontextualized manner. This is in line with the individualistic and independent values of Western cultures. Therefore, it is suggested that employing the sustainability framework emphasizing interdependencies within well-being research can be beneficial; perhaps even resulting in an all-inclusive increase in well-being. Limitations are also raised and future research directions suggested. The author concludes that both sustainability and well-being research can benefit from the synergy toward sustainable well-being.